The last major cruise line to hold out has cancelled its April 2021 cruises.

MSC Cruises announced it has cancelled its U.S.-based sailings through to and including April 30, 2021.

The announcement was made on Wednesday and affects three cruise ships:

MSC Cruises took delivery of a brand new cruise ship.

The MSC Virtuosa becomes the 18th ship to join MSC's fleet and was delivered to the cruise line at Chantiers de l’Atlantique in Saint Nazaire, France.

MSC says Virtuosa will be the most environmentally-conscious at sea when she comes into service in April.  

MSC Cruises announced it will join other cruise lines in cancelling its March 2021 cruises.

The announcement was made on Monday night and affects four cruise ships:

• MSC Seaside
• MSC Divina
• MSC Meraviglia
• MSC Armonia

The ships were scheduled to sail from Port Canaveral and Miami.

Guests booked on the cancelled cruises that were paid in full will have the choice of a full refund or a 125% future cruise credit that may be used on any ship and any itinerary through April 30, 2022.

MSC Cruises announced it will restart cruises from Italy later this month, and there will be newly enhanced health protocols onboard.

MSC will resume cruises in the Mediterranean beginning January 24 with the MSC Grandiosa. On February 14 MSC Magnifica will also return at sea to perform her scheduled itineraries of 11 nights in Italy, Greece and Malta.

In addition to the health protocols MSC cruise ships have been using on its ships since the summer, four new measures will be added:

MSC Cruises announced it would temporarily stop Mediterranean cruises on two of its ships due to new Italian government restrictions.

Sailings on MSC Grandiosa later this month are cancelled and the planned restart of MSC Magnifica has been moved to January.

MSC Cruises announced it would extend its suspension of U.S. cruises through the end of February 2021.

Like all the other major cruises lines, MSC will delay its restart plans for North America.

Three MSC cruise ships are affected by the announcement:

MSC Cruises announced on Thursday the current health crisis in Europe has forced them to shut down some cruises again.

MSC noted that significant restrictions of movement, in particular in France and Germany, forced the cruise line to temporarily suspend further sailings of MSC Magnifica from November 8 through to December 18, 2020. 

MSC Cruises announced on Monday it has cancelled its December 2020 cruises through to and including December 31, 2020.

The new round of cancellations affects three ships in Florida: MSC Seaside in Port Canaveral, and MSC Meraviglia and MSC Armonia both in PortMiami.

MSC Cruises announced the MSC Seashore cruise ship will be the first ship feature new advanced air sanitation technology aimed at reducing virus threat.

Dubbed "Safe Air", the new air sanitation system will be fitted on MSC Seashore, which is currently under construction at the Fincantieri’s Monfalcone yard.